A High Throughput Assay to Identify Small Molecule Modulators of Prostatic Acid Phosphatase

Table 1: Activities of Confirmed Inhibitors from Chemical Library using PAP Assay

Compound	Asinex Identifier^a	IC₅₀ (µM)^b
1	BAS 07119722	2.0
2	BAS 08865249	6.7
3	BAS 08863852	6.9
4	BAS 03013122	8.0
5	BAS 08862870	13.8
6	BAS 02830262	15.4
7	BAS 00669251	19.3

^a Chemical identifier number provided by Asinex Corporation.

^b For IC₅₀ determinations, serial dilutions of compounds were tested starting at a high concentration of 20 µM.