Improved Dual-Luciferase Reporter Assays for Nuclear Receptors

A) ER
Agonist	EC₅₀ (nM)	Induction
17β-estradiol (primary ligand)	0.025	2200
Estrone	7.2	900
Dihydro-testosterone	8500	630
Antagonist	IC₅₀ (nM)
Tamoxifen	2000
ICI 182,780	10
Raloxifene	47