Table 1: Example Randomization Number Format to Allow Replacement

Cohort	Original or Replacement Randomization List	Randomization Number Range
1	Original	1001 – 1048
	Replacement list 1	1101 – 1148
	Replacement list 2	1201 – 1248
2	Original	2001 – 2048
	Replacement list 1	2101 – 2148
	Replacement list 2	2201 – 2248