Fig. (3) (A) I9.2 cells stably transfected with wild type (WT) caspase 8 or caspase 8 with the RN mutation were infected with VSV-G pseudotyped HIV and analyzed for viability as a function of time by trypan blue exclusion. (B) The stably transfected I9.2 cells were infected with VSV-G pseudotyped HIV and analyzed for relative cell number 60 hours post-infection by ATP activity. (C) Cells harvested 60 hours post-infection were also assessed for casp8p41 content. Results are representative of three independent experiments.