Synthesis and Characterization of a Series of 1-Aryl-4-[aryldiazenyl]-
piperazines. Part I. Isomers of N-(2,3-Dimethylphenyl)-N’-(Aryldiazenyl)-
Piperazines
Chenguang Fan, Keith Vaughan*Department of Chemistry, Saint Mary’s University, Halifax, Nova Scotia, B3H 3C3, Canada
Abstract
This paper describes the synthesis of several new series of 1-(2-aryldiazen-1-yl-) 4-arylpiperazines and 1-(2-
aryldiazen-1-yl-)4-arylalkylpiperazines by using diazonium coupling between arenediazonium ions with the appropriate
1-arylpiperazine or the 1-arylalkylpiperazine. The new compounds have a common thread in that they are isomers of the
series of N-(2,3-dimethylphenyl)- N’-(aryldiazenyl)-piperazines. The new triazenes have been characterized by IR and
NMR spectroscopy and mass spectrometry.
Keywords: Arylpiperazine; diazonium ion, 1-(2,3-dimethylphenyl-)piperazine, IR spectroscopy, Mass spectrometry, 1-(2-
methylphenylmethyl-)piperazine, 1-(3-methylphenylmethyl-)piperazine, 1-(4-methylphenylmethyl-)piperazine, NMR
spectroscopy, piperazine, triazene.
Article Information
Article History:
Received Date: 2/2/2015
Revision Received Date: 6/4/2015
Acceptance Date: 7/4/2015
Electronic publication date: 30/10/2015
© Fan and Vaughan; Licensee Bentham Open.
open-access license:
This is an open access article licensed under the terms of the (
https://creativecommons.org/licenses/by/4.0/legalcode), which permits unrestricted, noncommercial
use, distribution and reproduction in any medium, provided the work is properly cited.
* Address correspondence to this author at the Department of Chemistry,
Saint Mary’s University, Halifax, Nova Scotia, B3H 3C3, Canada;
Tel: 902-420-5650; E-mail: keith.vaughan@smu.ca
Open Peer Review Details |
Manuscript submitted on 2-2-2015 |
Original Manuscript |
Synthesis and Characterization of a Series of 1-Aryl-4-[aryldiazenyl]-
piperazines. Part I. Isomers of N-(2,3-Dimethylphenyl)-N’-(Aryldiazenyl)-
Piperazines |