The Open AIDS Journal

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Population-Based Study of Risk Factors for Coronary Heart Disease Among HIV-Infected Persons

John Y Oh1, 2, Kari Greene2, Haiou He2, Sean Schafer*, 2, Katrina Hedberg2
1 Epidemic Intelligence Service, Centers for Disease Control and Prevention, Portland, Oregon, USA
2 Oregon Public Health Division, Portland, Oregon, USA


Preventing coronary heart disease (CHD) is critical to further extending survival among human immunodeficiency virus (HIV)-infected persons. Previously published findings of CHD risk factors in HIV-infected persons have been derived from facility-based cohort studies, which have limited representativeness for the HIV-infected population. State-specific, population-based surveillance data can assist health care providers and public health agencies in planning and evaluating programs that reduce CHD among HIV-infected persons. We describe CHD risk factors from the 2007-2008 Oregon Medical Monitoring Project, a population-based survey of HIV-infected persons receiving care that included both patient interview and medical record review. Among the 539 HIV-infected patients interviewed, the mean age was 45.5 years. Diagnoses from the medical record associated with CHD risk included preexisting CHD (5%), diabetes (11%), and hypertension (28%). Current smoking was reported by 46%; college graduates were less likely to smoke compared with those with lesser education (21% versus 53%, respectively; P <.0001). Obesity was present among 17%. Among the 65% of the survey group with lipid values available, 55% had high-density lipoprotein cholesterol (HDL) <40 mg/dL and 42% had triglycerides ≥ 200 mg/dL. Among the 15% of the survey group with either preexisting CHD or diabetes, 42% had a non-HDL <130 mg/dL (target goal) and 38% smoked. Risk factors for CHD among HIVinfected persons, particularly smoking and dyslipidemia, should be managed aggressively. Ongoing surveillance is warranted to monitor changes in CHD risk factors in the HIV-infected population.

Keywords: : Human immunodeficiency virus, coronary disease, risk factors, smoking, dyslipidemias..

Article Information

Identifiers and Pagination:

Year: 2012
Volume: 6
Issue: Suppl 1
First Page: 177
Last Page: 180
Publisher Id: TOAIDJ-6-177
DOI: 10.2174/1874613601206010177

Article History:

Received Date: 16/4/2011
Revision Received Date: 9/8/2011
Acceptance Date: 13/8/2011
Electronic publication date: 7/9/2012
Collection year: 2012

© Oh et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the HIV/STD/TB Program, Oregon Public Health Division, 800 NE Oregon St., Ste. 1105, Portland OR 97232, USA; Tel: 971-673-0153; Fax: 971-673-0179; E-mail:

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