Momordica charantia, commonly known as karela or bitter melon, is used as a vegetable in Chinese, Indian
subcontinent. However, in Chinese traditional medicine, the plant is usually used as an antidiabetic agent. One of the active
components is charantin. Aqueous two-phase systems (ATPS) were used for the purifying saponin because of their
low cost. ATPS can reduce amount of organic solvent and the danger of explosion necessitates special equipment leading
to increased costs. The levels of blood glucose decreased after administration of charantin purified from Momordica
charantia with (ATPS (p<0.05).