- Home
- About Journals
-
Information for Authors/ReviewersEditorial Policies
Publication Fee
Publication Cycle - Process Flowchart
Online Manuscript Submission and Tracking System
Publishing Ethics and Rectitude
Authorship
Author Benefits
Reviewer Guidelines
Guest Editor Guidelines
Peer Review Workflow
Quick Track Option
Copyediting Services
Bentham Open Membership
Bentham Open Advisory Board
Archiving Policies
Fabricating and Stating False Information
Post Publication Discussions and Corrections
Editorial Management
Advertise With Us
Funding Agencies
Rate List
Kudos
General FAQs
Special Fee Waivers and Discounts
- Contact
- Help
- About Us
- Search
The Open Bioactive Compounds Journal
(Discontinued)
ISSN: 1874-8473 ― Volume 9, 2020
Analysis of Raspberry Ketone in Nutraceutical Formulation Using Fourier Transform Infrared Spectrophotometric Method
Hassan Y. Aboul-Enein1, *, Oana Mihaela Antochi2, 3, Gheorghe Nechifor3, Andrei A. Bunaciu4
Abstract
Aims:
A Fourier Transform Infrared (FT-IR) spectrometric method was developed for the rapid, direct measurement of Raspberry Ketone (RK) and Caffeine (CAF) in a nutraceutical formulation.
Methods:
Conventional KBr-spectra and KBr+0.5 mg Microcrystalline Cellulose (MCC)-spectra were used as the basis for a better determination of active substances in the nutraceutical formulation. A calibration model was developed using caffeine and raspberry ketone standards of varying concentrations in the mid-infrared region (4000-400 cm-1). The Beer-Lambert law was used in data processing.
Results:
The results indicate that FT-IR spectrometry is applicable to the analytical quantification of RK and CAF in the nutraceutical formulation.
Conclusion:
The method proposed is simple, precise and not time-consuming compared to the chromatographic methods that are cited in the literature. Quantification is performed in about 10-15 minutes, including sample preparation and spectral acquisition.
Article Information
Identifiers and Pagination:
Year: 2019Volume: 7
First Page: 8
Last Page: 13
Publisher Id: TOBCJ-7-8
DOI: 10.2174/1874847301907010008
Article History:
Received Date: 09/07/2019Revision Received Date: 27/09/2019
Acceptance Date: 17/10/2019
Electronic publication date: 05/12/2019
Collection year: 2019
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
* Address correspondence to this author at the Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, Dokki, Cairo 12622, Egypt; Tel: +00201003678948; Fax: +0020233370931;
E-mail: haboulenein@yahoo.com
| Open Peer Review Details | |||
|---|---|---|---|
| Manuscript submitted on 09-07-2019 |
Original Manuscript | Analysis of Raspberry Ketone in Nutraceutical Formulation Using Fourier Transform Infrared Spectrophotometric Method | |