RETRACTED ARTICLE
The Influence of Corn Silk Polysaccharide on Signal Pathway of TGF-β1 in Type 2 Diabetic Mellitus Rat
Xianchun Wen*, Liling Yue
Article Information
Identifiers and Pagination:
Year: 2015Volume: 9
First Page: 204
Last Page: 208
Publisher ID: TOBEJ-9-204
DOI: 10.2174/1874120701509010204
Article History:
Received Date: 10/04/2015Revision Received Date: 20/05/2015
Acceptance Date: 15/06/2015
Electronic publication date: 31/8/2015
Collection year: 2015
open-access license: This is an open access article licensed under the terms of the (https://creativecommons.org/licenses/by/4.0/legalcode), which permits unrestricted, noncommercial use, distribution and reproduction in any medium, provided the work is properly cited.
Abstract
The study performed some experiments and made following conclusions. In the prevention stage, comparing with normal control group, triglycerides, blood sugar (BG), 24-hour urinary protein and cholesterol (CHO) were higher in T2DM group, but weight and urea nitrogen (BUN) was less in that group. 24-hour urinary protein and cholesterol (CHO) were higher in T2DM group than the intervention group. 24-hour urinary protein and BG in the intervention group were also observed to be higher than the normal control group, but BUN was less than the normal control group. In the intervention group, the weight of kidney and the weight of rat were also higher than T2DM group, but CHO and 24-hour urinary protein were less than T2DM group. The expression of TGF-β1 in T2DM group was also observed to be more than the other groups. However, in the treatment stage, serum creatinine (Cr), weight, BG and CHO, TGand 24-hour urinary protein were significantly higher in the DN rats than those in the normal control rats (P>0.05). The expression level of TGF-β1 and triglyceride level in the corn silk dihydroxycorn silk3 treated group were noticeably lower than those in the DN rats.