Indices Indicating Early Renal Microvascular Disease in Diabetes

Futrakul, N.; Futrakul, P.

Indices Indicating Early Renal Microvascular Disease in Diabetes

N. Futrakul^{*, 1}, P. Futrakul²

¹ Renal Microcirculation Research Group, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand

² Academy of Science, The Royal Institute of Thailand

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Identifiers and Pagination:

Year: 2011
Volume: 4
First Page: 18
Last Page: 20
Publisher ID: TOBIOMJ-4-18
DOI: 10.2174/1875318301104010018

Article History:

Received Date: 15/09/2011
Revision Received Date: 26/10/2011
Acceptance Date: 29/10/2011
Electronic publication date: 28/12/2011
Collection year: 2011

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© 2011 Futrakul

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

^* Address correspondence to this author at the Renal Microcirculation Research Group, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand; Tel: 60813511214; Fax: 022584267; E-mail: fmednft@yahoo.com

Renal microvascular disease is crucial to renal disease progression. Renal microvascular disease in late stage diabetic nephropathy is associated with defective angiogenesis and fails to respond to vasodilator treatment. Recognition of early renal microvascular disease is necessary, since in this stage, the vascular homeostasis is adequately functional and responsive to vasodilator treatment. Indices that can screen early renal microvascular disease include creatinine clearance or glomerular filtration rate, renal plasma flow or peritubular capillary flow and fractional excretion of magnesium (FE Mg).

Keywords: Renal microvascular disease, Diabetes, Vascular homeostasis, Renal hemodynamics, FE Mg.

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RESEARCH ARTICLE

Indices Indicating Early Renal Microvascular Disease in Diabetes

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