Capillary Electrophoresis Coupled To Mass Spectrometry for Forensic Analysis

Huck, Christian W.; Huck-Pezzei, Verena; Bakry, Rania; Bachmann, Stefan; Najam-ul-Haq, Muhammad; Rainer, Matthias; Bonn, Günther K.

Capillary Electrophoresis Coupled To Mass Spectrometry for Forensic Analysis

Christian W. Huck^*, Verena Huck-Pezzei, Rania Bakry, Stefan Bachmann, Muhammad Najam-ul-Haq, Matthias Rainer, Günther K. Bonn

Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University, Innrain 52a, 6020 Innsbruck, Austria

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Identifiers and Pagination:

Year: 2007
Volume: 1
First Page: 30
Last Page: 43
Publisher ID: TOCENGJ-1-30
DOI: 10.2174/1874123100701010030

Article History:

Received Date: 20/07/2007
Revision Received Date: 03/10/2007
Acceptance Date: 16/11/2007
Electronic publication date: 3/11/2007
Collection year: 2007

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© 2007 Huck et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

^* All correspondence to this author at the Oral Surgery Department, Faculty of Dentistry, Universitas Padjadjaran, Jl. Sekeloa Selatan no. 1, Bandung 40132, West Java – Indonesia; Tel: +(62)-82115513030; E-mails: Christian.w.huck@uibk.ac.at

In this review the most important techniques, which are developed to hyphenate capillary electrophoresis to mass spectrometry (CE-MS), suitable for forensic analysis, are summarized. Analytes of interest are divided into four main parts, namely, compounds with amine containing side chains, compounds with N-containing saturated ring structures, other heterocycles and peptides. Sample pre-treatments and direct injection modes used in CE-MS for forensic analysis are briefly discussed from critical point of view. Special emphasis is placed to point out the advantages of mass spectrometric detection compared to UV- and laser- induced fluorescence (LIF) detections.

Keywords: Capillary electrophoresis, mass spectrometry, forensic, review, drugs.

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RESEARCH ARTICLE

Capillary Electrophoresis Coupled To Mass Spectrometry for Forensic Analysis

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