RESEARCH ARTICLE
High-Pressure Vapor-Liquid Equilibrium Data for Ternary Systems CO2 + Organic Solvent + Curcumin
Willyan M. Giufrida1, Rogério Favareto1, Vladimir F. Cabra1, M. Angela A. Meireles3, Lucio Cardozo-Filho*, 1, Marcos L. Corazza2
Article Information
Identifiers and Pagination:
Year: 2010Volume: 4
First Page: 3
Last Page: 10
Publisher ID: TOCENGJ-4-3
DOI: 10.2174/1874123101004010003
Article History:
Received Date: 15/08/2009Revision Received Date: 06/11/2009
Acceptance Date: 08/12/2009
Electronic publication date: 25/3/2010
Collection year: 2010
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
In the present work phase equilibrium data for the ternary systems CO2 + ethanol + curcumin and CO2 + ethyl acetate + curcumin, at different concentrations of curcumin in the organic solvent (0.01 g.cm-3, 0.005 g.cm-3 for ethanol and 0.01 g.cm-3, 0.0025 g.cm-3 for ethyl acetate) are reported. The static synthetic method, using a variable-volume view cell was employed for obtaining the experimental data in the temperature range of (303 to 333) K and pressures up to 11 MPa. Vapor-liquid phase transitions were observed as bubble and dew points for the overall compositions investigated. The phase equilibria of the ternary systems were fitted to the Peng-Robinson equation of state (PR-EoS) using only binary system information. Experimental data together with modeling results may constitute relevant information for the precipitation of curcumin using the supercritical antisolvent process.