The Open Cardiovascular Medicine Journal




ISSN: 1874-1924 ― Volume 14, 2020

Ictal Cardiac Ryhthym Abnormalities



Rushna Ali*
Henry Ford Hospital, Department of Neurosurgery, 2799 West Grand Blvd. Detroit, MI 48202, USA

Abstract

Cardiac rhythm abnormalities in the context of epilepsy are a well-known phenomenon. However, they are under-recognized and often missed. The pathophysiology of these events is unclear. Bradycardia and asystole are preceded by seizure onset suggesting ictal propagation into the cortex impacting cardiac autonomic function, and the insula and amygdala being possible culprits. Sudden unexpected death in epilepsy (SUDEP) refers to the unanticipated death of a patient with epilepsy not related to status epilepticus, trauma, drowning, or suicide. Frequent refractory generalized tonic-clonic seizures, anti-epileptic polytherapy, and prolonged duration of epilepsy are some of the commonly identified risk factors for SUDEP. However, the most consistent risk factor out of these is an increased frequency of generalized tonic–clonic seizures (GTC). Prevention of SUDEP is extremely important in patients with chronic, generalized epilepsy. Since increased frequency of GTCS is the most consistently reported risk factor for SUDEP, effective seizure control is the most important preventive strategy.

Keywords: Bradycardia, cardiac arrest, epilepsy, sudden unexplained death in epilepsy (SUDEP).


Article Information


Identifiers and Pagination:

Year: 2016
Volume: 10
Issue: Suppl-1, M5
First Page: 105
Last Page: 109
Publisher Id: TOCMJ-10-105
DOI: 10.2174/1874192401610010105

Article History:

Received Date: 22/8/2015
Revision Received Date: 20/9/2015
Acceptance Date: 22/10/2015
Electronic publication date: 27/05/2016
Collection year: 2016

© Rushna Ali; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.


* Address correspondence to this author at the Department of Anatomy, College of Medicine and Health Sciences, Afe Henry Ford Hospital, Department of Neurosurgery, 2799 West Grand Blvd. Detroit, MI 48202, USA; Tel: (313)-400-5520; Email: rali1@hfhs.org



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