Insights in Hypothesis Testing and Making Decisions in Biomedical Research

Sacha, Varin; Panagiotakos, Demosthenes B.

Insights in Hypothesis Testing and Making Decisions in Biomedical Research

Varin Sacha¹, Demosthenes B. Panagiotakos^{2, *}

¹ Collège de Villamont, Lausanne, Switzerland

² School of Health Science and Education, Harokopio University, Athens, Greece

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Identifiers and Pagination:

Year: 2016
Volume: 10
First Page: 196
Last Page: 200
Publisher ID: TOCMJ-10-196
DOI: 10.2174/1874192401610010196

Article History:

Received Date: 2/12/2015
Revision Received Date: 22/2/2016
Acceptance Date: 5/3/2016
Electronic publication date: 30/09/2016
Collection year: 2016

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© Sacha et al.; Licensee Bentham Open

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

^* Address correspondence to this author at the 46 Paleon Polemiston St. Glyfada, Attica, 166 74, Greece; Tel.: +30210-9603116; Fax: +30210-9600719; E-mail: d.b.panagiotakos@usa.net

It is a fact that p values are commonly used for inference in biomedical and other social fields of research. Unfortunately, the role of p value is very often misused and misinterpreted; that is why it has been recommended the use of resampling methods, like the bootstrap method, to calculate the confidence interval, which provides more robust results for inference than does p value. In this review a discussion is made about the use of p values through hypothesis testing and its alternatives using resampling methods to develop confidence intervals of the tested statistic or effect measure.

Keywords: Biostatistics, Confidence intervals, Evidence based medicine, p value, Resampling.

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RESEARCH ARTICLE

Insights in Hypothesis Testing and Making Decisions in Biomedical Research

Article Information

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Article History:

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Abstract

Track Your Manuscript

Published Contents

About the Editor

About the Journal

The Open Cardiovascular Medicine Journal

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Unique Views/Downloads: 135,933

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