The Open Dentistry Journal




ISSN: 1874-2106 ― Volume 13, 2019

Antibacterial Activity of Copaiba Oil Gel on Dental Biofilm



Cláudia A.C.G. Simões1, Nikeila C. de Oliveira Conde2, Gisely N. Venâncio3, Patrícia S.L.L. Milério4, Maria F.C.L. Bandeira5, *, Valdir F. da Veiga Júnior6
1 Department of Dental Materials, College of Dentistry, UFAM – Federal University of Amazonas, Manaus, AM, Brazil
2 Department of Stomatology and Phytotherapy, College of Dentistry, UFAM – Federal University of Amazonas, Manaus, AM, Brazil
3 Department of Stomatology and Phytotherapy, College of Dentistry, UFAM – Federal University of Amazonas, Manaus, AM, Brazil
4 Department of Phytotherapy, College of Dentistry, UFAM – Federal University of Amazonas, Manaus, AM, Brazil
5 Department of Dentistry and Phytotherapy, College of Dentistry, UFAM – Federal University of Amazonas, Manaus, AM, Brazil
6 School of Chemistry - Federal University of Amazonas, Manaus, AM, Brazil

Abstract

Amazonian biodiversity products that have been used for years in folk medicine, have emerged as feasible and promising alternatives for the inhibition of microorganisms in dental biofilm. Copaiba oil, a phytotherapic agent widely used by the Amazonian populations, is known for its antibacterial, anti-inflammatory, anesthetic, healing and antitumor medicinal properties.

Objective:

The aim of this study was to evaluate the in vitro antibacterial activity of copaiba oil (Copaifera multijuga) gel against strains of Streptococcus sp present in dental biofilm.

Materials and Methods:

The copaiba oil was obtained and the chemical components were identified. The oil emulsions were formulated and used with the Brain Heart Infusion agar diffusion method with strains of Streptococcus mitis, Streptococcus constellatus and Streptococcus salivarius isolated from patients as well as standard strains of S. mitis (ATCC903), S. mutans (ATCC10449), S. sanguinis (ATCC15300) and S. oralis (ATCC10557). The study groups were as follows: experimental copaiba oil gel, 1% chlorhexidine gel (positive control) and base gel (negative control). The seeded plates were incubated at 37ºC for 12, 24 and 48 hours, respectively. The results obtained were analyzed by Shapiro-Wilk and Friedman Tests (p<0.05) for non parametric data and the Tukey test was used for pH values with 5% level of significance.

Results:

The experimental copaiba oil gel and 1% chlorhexidine gel showed antibacterial activity against the tested microorganisms.

Conclusion:

The copaiba oil gel demonstrated antibacterial activity against all the strains of Streptococcus sp tested, suggesting that it can be used for dental biofilm control.

Keywords: Alternative medicine, biofilm, Copaifera, phytotherapy, Streptococcus.


Article Information


Identifiers and Pagination:

Year: 2016
Volume: 10
Issue: Suppl-1, M6
First Page: 188
Last Page: 195
Publisher Id: TODENTJ-10-188
DOI: 10.2174/1874210601610010188

Article History:

Received Date: 30/12/2015
Revision Received Date: 10/1/2016
Acceptance Date: 28/1/2016
Electronic publication date: 11/05/2016
Collection year: 2016

Article Metrics:

CrossRef Citations:
0

Total Statistics:

Full-Text HTML Views: 1452
Abstract HTML Views: 1156
PDF Downloads: 251
ePub Downloads: 168
Total Views/Downloads: 3027

Unique Statistics:

Full-Text HTML Views: 704
Abstract HTML Views: 546
PDF Downloads: 157
ePub Downloads: 120
Total Views/Downloads: 1527
Geographical View

© Simões et al. ; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.


* Address correspondence to this author at the Department of Dentistry and Phytotherapy, College of Dentistry, UFAM – Federal University of Amazonas, Manaus, AM, Brazil; E-mail: fulgencia@ufam.edu.br


Endorsements



"Thank you for your magnificent and marvelous support throughout the publication stages. I would like to endorse my experience with you as a Junior Researcher and a recent graduate of the Dental school. Once again Thank you for your Great Help and Guidance throughout the stages of Publication. You guys are a great team and I am proud to be a Young Bentham author."


Asra Sabir Hussain
The University of Edinburgh Business School, UK

"My experience with Bentham Open was a valuable one because the quality of the services and analysis of my paper contributed in improving what we intended to convey to the readers."


José Ricardo Kina
Department of Surgery and Integrated Clinic,
Araçatuba School of Dentistry, São Paulo State University
Brazil

"The Publication Manager was very cooperative and replied my mails and guided me without any delays; however the reviewing process was too long."


Mahtab Memarpour
Prevention of Oral and Dental Disease Research Center,
Department of Pediatric Dentistry, School of Dentistry,
Shiraz University of Medical Sciences, Shiraz,
Iran


Browse Contents



Webmaster Contact: info@benthamopen.net
Copyright © 2019 Bentham Open