The Open Dentistry Journal




ISSN: 1874-2106 ― Volume 13, 2019

Diagnosis and Intralesional Corticotherapy in Oral Ulcers Occurring as the Sole Manifestation of Langerhans Cell Histiocytosis. A Case Report



Liane Gambirazi, Tatiana Libório, Fábio Nunes, Norberto Sugaya, Dante Migliari*
Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil

Abstract

This article reports a case of oral mucosa lesions as the sole manifestation in Langerhans cell histiocytosis (LCH). This is a very uncommon manifestation of LCH since this disease preferably affects the bones with frequent involvement of the jaws. LCH may also involve other organs, particularly the lungs, liver, lymph nodes, and skin. The highlights of this report are the differential diagnosis, immunohistochemical analysis and, mostly, the therapeutic approach.

Keywords: Diagnosis, Intralesional corticotherapy, Langerhans cell histiocytosis, Oral ulcers.


Article Information


Identifiers and Pagination:

Year: 2016
Volume: 10
First Page: 330
Last Page: 337
Publisher Id: TODENTJ-10-330
DOI: 10.2174/1874210601610010330

Article History:

Received Date: 31/12/2015
Revision Received Date: 04/05/2016
Acceptance Date: 09/05/2016
Electronic publication date: 25/06/2016
Collection year: 2016

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© Gambirazi et al; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.


* Address correspondence to this author at the Universidade de São Paulo, Faculdade de Odontologia, Departamento de Estomatologia, Av: Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, SP 05508-900, Brazil; Tel/Fax: +55 11 30917901; E-mail: damiglia@usp.br


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Department of Surgery and Integrated Clinic,
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Brazil

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Mahtab Memarpour
Prevention of Oral and Dental Disease Research Center,
Department of Pediatric Dentistry, School of Dentistry,
Shiraz University of Medical Sciences, Shiraz,
Iran


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