The Open Dentistry Journal

ISSN: 1874-2106 ― Volume 14, 2020

Health Complaints Attributed to Dental Amalgam: A Retrospective Survey Exploring Perceived Health Changes Related to Amalgam Removal

Agnete Egilsdatter Kristoffersen1, *, Terje Alræk1, Trine Stub1, Harald Johan Hamre2, Lars Björkman3, Frauke Musial1
1 The National Research Center in Complementary and Alternative Medicine (NAFKAM), Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway
2 Institute for Applied Epistemology and Medical Methodology at the University of Witten-Herdecke, Freiburg, Germany
3 Dental Biomaterials Adverse Reaction Unit, Uni Research Health, Bergen, Norway



Many patients have complex health complaints they attribute to dental amalgam. There is some evidence of symptom relief after removal of amalgam.


The aims of this study were to assess the total symptom load in patients with all their amalgam fillings removed, and to investigate the self-reported improvement of health with regard to precautions taken under amalgam removal and time since removal.


The survey was distributed to all members (n=999) of the Norwegian Dental patients association in 2011. The study participants returned the questionnaires anonymously by means of a pre-stamped envelope. The questionnaire asked for sociodemographic data, subjectively perceived health status, complaints persisting after amalgam removal and self-reported changes in symptoms after amalgam removal.


A total of 324 participants were included in the study. The majority of the participants reported improved health after amalgam removal, even though the mean degree of severity of complaints was still high. Exhaustion and musculoskeletal complaints were most severe, and reflects the fact that 38% of the participants reported poor to very poor current health. With regard to amalgam removal, associations between improved health, number of precautions applied, and time since removal were found.


Most of the participants in this study reported improvement of health after amalgam removal even though they still suffered a high complaint load. Since absolute symptom load is a robust predictor for general health outcome and socioeconomic burden for society, a possible intervention, which enables patients to further improve their health status is desirable.

Keywords: Dental amalgam, Health complaints, Mercury, Restoration.

Article Information

Identifiers and Pagination:

Year: 2016
Volume: 10
First Page: 739
Last Page: 751
Publisher Id: TODENTJ-10-739
DOI: 10.2174/1874210601610010739

Article History:

Received Date: 28/06/2016
Revision Received Date: 06/12/2016
Acceptance Date: 12/12/2016
Electronic publication date: 30/12/2016
Collection year: 2016

© Kristoffersen et al.; Licensee Bentham Open

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the National Research Center in Complementary and Alternative Medicine, NAFKAM, Department of Community Medicine, Faculty of Health Science, UiT The Arctic University of Norway 9037 Tromsø, Norway; Tel: (+47) 77 64 61 47; Fax: (+47) 77 64 68 66; E-mail:


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