The Open Dentistry Journal




ISSN: 1874-2106 ― Volume 13, 2019
RESEARCH ARTICLE

Anxiety and Salivary Level of Alpha-Amylase in Patients with Geographic Tongue: A Case Control Study



Atefeh Tavangar1, Zahra Saberi2, Maryam Rahimi3, Fahimeh Pakravan4, *
1 Dental Materials Research Center, Department of Oral Medicine, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
2 Dental Research Center, Department of Oral Medicine, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
3 School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
4 Dental Implant Research Center, Department of Oral Medicine, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Background:

Geographic tongue is a common benign condition involving the tongue with an unknown etiology.

Objective:

This study aimed to measure the salivary level of alpha-amylase as well as the level of anxiety of patients with geographic tongue.

Methods:

This case-control study was performed on 180 subjects including 89 patients with geographic tongue and 91 controls. The subjects were requested to fill out the Spielberger’s State-Trait Anxiety Inventory (STAI-S, STAI-T). Unstimulated saliva samples were collected by the spitting method to assess the salivary level of alpha-amylase. Data were analyzed using SPSS version 23, t-test and Pearson’s test (α=0.05).

Results:

The mean salivary level of alpha-amylase and the mean scores of state and trait anxiety in geographic tongue patients were higher than those of healthy controls. But these differences did not reach statistical significance (P>0.05).

Conclusion:

Anxiety may be an influential factor in the occurrence of geographic tongue. Salivary level of alpha-amylase cannot serve as a specific biomarker for assessment of geographic tongue.

Keywords: Alpha-amylase, Geographic tongue, Anxiety, Saliva, Biomarker, Filiform papillae.


Article Information


Identifiers and Pagination:

Year: 2019
Volume: 13
First Page: 209
Last Page: 213
Publisher Id: TODENTJ-13-209
DOI: 10.2174/1874210601913010209

Article History:

Received Date: 08/03/2019
Revision Received Date: 22/04/2019
Acceptance Date: 23/05/2019
Electronic publication date: 30/05/2019
Collection year: 2019

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© 2019 Tavangar et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


* Address correspondence to this author at the Dental Implant Research Center, Department of Oral Medicine, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran; Tel: +98-9131067247; Email: pakravanfahimeh@yahoo.com


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