The Open Dentistry Journal

ISSN: 1874-2106 ― Volume 11, 2017

Long-term Caries Preventive Effects of a School-Based Fluoride Mouth Rinse Program in Adulthood

Y Neko-Uwagawa, A Yoshihara*, H Miyazaki
Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Japan


The purpose of this study was to evaluate the long-term caries preventive effects of school-based fluoride mouth rinse (FMR) program in adults aged 20 years and older. 637 mothers aged from 20 to 39 years were surveyed. Clinical examinations were carried out for subjects to obtain data on dental caries prevalence when they visited local health centers to take their children for medical and dental check-ups at 1.5- or 3-years old. We also obtained information regarding the FMR program: the duration that the subjects participated between nursery school and junior high school. When analyzing data, subjects were divided into 4 groups: FMR from nursery to junior high school group (N-JH group, n=22), FMR limited to the elementary school group (El group, n=62), FMR no-experience group (n=545), and other subjects whose FMR experience is not clear (n=8). For evaluation of the FMR program effect, multiple regression analysis was used. As independent variable, the FMR program patterns were converted into dummy data, and mean DMFT was used as dependent variable. The results of multiple regression analysis between mean DMFT and FMR program patterns showed that the N-JH group and El group were negatively associated with the mean DMFT (ß=-0.20, p<0.001 for N-JH group and ß=-0.11, p=0.003 for El group).

The positive caries preventive effects of school-based FMR program from nursery school to junior high school can continue in adults aged 20 years and older.

Key Words: Fluoride mouth rinse, Long-term effects, Dental caries, Adulthood.

Article Information

Identifiers and Pagination:

Year: 2011
Volume: 5
First Page: 24
Last Page: 28
Publisher Id: TODENTJ-5-24
DOI: 10.2174/1874210601105010024

Article History:

Received Date: 3/9/2010
Revision Received Date: 14/12/2010
Acceptance Date: 12/1/2011
Electronic publication date: 7/3/2011
Collection year: 2011

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© Neko-Uwagawa et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, 2-5274 Cho-ku Gakkocho-Dori, Niigata 951-8514, Japan; Tel: +81 25 227 2858; Fax: +81 25 227 0807; E-mail:


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