The Open Dentistry Journal




ISSN: 1874-2106 ― Volume 13, 2019

Effects on Dentin Treated with Eluted Multi-Mineral Varnish In Vitro



Robert L Karlinseya, * , Allen C Mackeya, Craig S Schwandtb
a Indiana Nanotech, 351 West 10th Street, Suite 309, Indianapolis, Indiana, 46202, USA
b McCrone Associates, Inc., 850 Pasquinelli Drive, Westmont, IL 60559-5539, USA

Abstract

Purpose:

The purpose of this pilot study was to assess the non-contact effects of a NaF varnish on the morphology and elemental compositions of sound and demineralized dentin in an in vitro pH cycling model.

Methods:

3 mm diameter dentin cores were extracted from bovine teeth, mounted in acrylic rods, and ground and polished. Sound and demineralized (in 10 mL unstirred 50% citric acid (pH = 1.2) for two minutes) specimens were divided into four groups (N=6) corresponding to treatments with either water (control group) or non-contact Vanish® 5% NaF White Varnish with tri-calcium phosphate (3M ESPE). For the non-contact varnish group, one 0.50 ml unit-dose was applied to acrylic rods and positioned in the same stopper as three dentin specimens. The four groups were then cycled in a regimen consisting of three rounds of one-hour treatments with each round followed by immersion in a three-minute static acid challenge (0.3% citric acid, pH = 3.8). For each one-hour treatment immersion the test groups were immersed in distilled water. The specimens were thoroughly rinsed with distilled water after each treatment and after each acid challenge. After the last challenge, specimens were rinsed with distilled water and immersed in artificial saliva (AS) overnight. All treatments, acid challenges and immersion in AS solution were performed in an incubator set at 37°C. After three days, the specimens were assessed using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS).

Results:

SEM and EDS results demonstrated the non-contact varnish group can provide mineralization benefits relative to the control group for both sound and demineralized dentin substrates. Depositions from mineral eluting from the varnish developed on the intertubular and intratubular regions alike, with the most prominent depositions appearing on initially demineralized dentin.

Conclusions:

In this observational study, acid-resistant mineral depositions were produced on the sound and dentin surfaces without direct application from a multi-mineral varnish containing fluoride, calcium and phosphate.

Keywords:: TCP, NaF, pH cycling, remineralization.


Article Information


Identifiers and Pagination:

Year: 2012
Volume: 6
First Page: 157
Last Page: 163
Publisher Id: TODENTJ-6-157
DOI: 10.2174/1874210601206010157

Article History:

Received Date: 25/6/2012
Revision Received Date: 2/8/2012
Acceptance Date: 2/8/2012
Electronic publication date: 5/10/2012
Collection year: 2012

Article Metrics:

CrossRef Citations:
0

Total Statistics:

Full-Text HTML Views: 1344
Abstract HTML Views: 952
PDF Downloads: 313
Total Views/Downloads: 2609

Unique Statistics:

Full-Text HTML Views: 795
Abstract HTML Views: 571
PDF Downloads: 222
Total Views/Downloads: 1588
Geographical View

© Karlinsey et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.


* Address correspondence to this author at the Indiana Nanotech, 351 West 10th Street, Suite 309, Indianapolis, Indiana, 46202, USA; Tel: +1-317-385-1578; Fax: +1317-278-4102; E-mail: rlk.nanotech@gmail.com


Endorsements



"Thank you for your magnificent and marvelous support throughout the publication stages. I would like to endorse my experience with you as a Junior Researcher and a recent graduate of the Dental school. Once again Thank you for your Great Help and Guidance throughout the stages of Publication. You guys are a great team and I am proud to be a Young Bentham author."


Asra Sabir Hussain
The University of Edinburgh Business School, UK

"My experience with Bentham Open was a valuable one because the quality of the services and analysis of my paper contributed in improving what we intended to convey to the readers."


José Ricardo Kina
Department of Surgery and Integrated Clinic,
Araçatuba School of Dentistry, São Paulo State University
Brazil

"The Publication Manager was very cooperative and replied my mails and guided me without any delays; however the reviewing process was too long."


Mahtab Memarpour
Prevention of Oral and Dental Disease Research Center,
Department of Pediatric Dentistry, School of Dentistry,
Shiraz University of Medical Sciences, Shiraz,
Iran


Browse Contents



Webmaster Contact: info@benthamopen.net
Copyright © 2019 Bentham Open