RESEARCH ARTICLE

Growth Hormone and Craniofacial Tissues. An update

George Litsas, * Open Modal Authors Info & Affiliations
The Open Dentistry Journal 30 Jan 2015 RESEARCH ARTICLE DOI: 10.2174/1874210601509010001

Abstract

Growth hormone is an important regulator of bone homeostasis. In childhood, it determines the longitudinal bone growth, skeletal maturation, and acquisition of bone mass. In adulthood, it is necessary to maintain bone mass throughout life. Although an association between craniofacial and somatic development has been clearly established, craniofacial growth involves complex interactions of genes, hormones and environment. Moreover, as an anabolic hormone seems to have an important role in the regulation of bone remodeling, muscle enhancement and tooth development. In this paper the influence of growth hormone on oral tissues is reviewed.

Keywords: Growth Hormone, Insulin-Like Growth Factor-I, Growth Hormone Receptor.
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