The Open Dentistry Journal




ISSN: 1874-2106 ― Volume 13, 2019

Growth Hormone and Craniofacial Tissues. An update



George Litsas*
Orthodontist 2, Venizelou Str. Kozani, Greece

Abstract

Growth hormone is an important regulator of bone homeostasis. In childhood, it determines the longitudinal bone growth, skeletal maturation, and acquisition of bone mass. In adulthood, it is necessary to maintain bone mass throughout life. Although an association between craniofacial and somatic development has been clearly established, craniofacial growth involves complex interactions of genes, hormones and environment. Moreover, as an anabolic hormone seems to have an important role in the regulation of bone remodeling, muscle enhancement and tooth development. In this paper the influence of growth hormone on oral tissues is reviewed.

Keywords: Growth Hormone, Insulin-Like Growth Factor-I, Growth Hormone Receptor.


Article Information


Identifiers and Pagination:

Year: 2015
Volume: 9
First Page: 1
Last Page: 8
Publisher Id: TODENTJ-9-1
DOI: 10.2174/1874210601509010001

Article History:

Received Date: 4/11/2014
Revision Received Date: 8/12/2014
Acceptance Date: 11/12/2014
Electronic publication date: 30 /1/2015
Collection year: 2015

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© George Litsas; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.


* Address correspondence to this author at the Orthodontist 2, Venizelou Str. Kozani, Greece; Tel: +30 24610 40087; Fax: +30 24610 41075; E-mail: info@orthodontics-clinic.gr


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Prevention of Oral and Dental Disease Research Center,
Department of Pediatric Dentistry, School of Dentistry,
Shiraz University of Medical Sciences, Shiraz,
Iran


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