RESEARCH ARTICLE


Epiluminescence Image Processing for Melanocytic Skin Lesion Diagnosis Based on 7-Point Check-List: A Preliminary Discussion on Three Parameters



Gabriella Fabbrocini*, 1, Giovanni Betta2, Giuseppe Di Leo3, Consolatina Liguori3, Alfredo Paolillo3, Antonio Pietrosanto3, Paolo Sommella3, Orsola Rescigno1, Sara Cacciapuoti1, Francesco Pastore1, Valerio De Vita1, Ines Mordente1, Fabio Ayala1
1 Dept of Systematic Pathology 􀀁 Section of Dermatology. University Federico II of Naples, Italy
2 Dept of Automation, Electromagnetism, Computer Science and Industrial Mathematics (DAEIMI), University of Cassino, Italy
3 Dept of Information and Electrical Engineering (DIIIE), University of Salerno, Italy


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Creative Commons License
© 2010 Fabbrocini et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Dept of Systematic Pathology, Section of Dermatology. University Federico II of Naples, Via Pansini, 5 80131 Naples, Italy; Tel: 0039-0817464386; Fax: 0039- 0817462442; E-mail: gafabbro@unina.it


Abstract

Epiluminescence microscopy (ELM) is a non-invasive technique used to enhance visualization of microscopic structures of pigmented lesions for the early detection of melanoma. The 7-point check-list is a diagnostic method that requires the identification of only seven dermoscopic criteria, defining the image through the use of algorithms. This paper describes an experimental automated diagnosis set-up of melanocytic skin lesions through an image processing methodology focused on finding the presence of different epiluminescence parameters. In this paper the image processing set-up allows the automatic detection of some specific dermoscopic criteria. We analyze the blue whitish veil, the regression, and the irregular streaks. The procedure developed was tested by considering a set of about 200 ELM images. A good concordance between ELM 7-point checklist parameters detected and the new method of image processing was achieved by kappa analysis. Although ELM doesn’t substitute histological evaluation, it could be a reliable instrument to enhance clinical accuracy of skin pigmented lesions diagnosis.

Keywords: Epiluminescence, 7-point check-list, blue whitish veil, regression structures, irregular streaks, image processing, melamoma diagnosis.