RESEARCH ARTICLE


Current Trends in Photoprotection - A New Generation of Oral Photoprotectors



Salvador Gonzalez*, 1, 2, Yolanda Gilaberte3, Neena Philips4, Angeles Juarranz5
1 Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, USA
2 Dermatology Service, Ramon y Cajal Hospital, Madrid, Spain
3 Dermatology Service, Hospital San Jorge, Huesca, Spain
4 School of Natural Sciences, University College, Fairleigh Dickinson University, Teaneck, NJ, USA
5 Biology Department, Sciences School, Universidad Autónoma de Madrid, Madrid, Spain


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Creative Commons License
© 2011 Gonzalez et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Dermatology Service, Memorial Sloan-Kettering Cancer Center, 160 East 53rd Street, New York, NY-10022 USA; Tel: 212 610 0185; Fax: 212 308 0530; E-mail: gonzals6@mskcc.org


Abstract

This review provides an overview of important concepts and trends in photoprotection. From the use of protective clothing to latest-generation oral photoprotectives, this article covers these topics from two points of view: 1) the physical blockade (absorption and/or reflection) of UV photons by topical sunscreens; 2) topical compounds with antioxidant properties that thereby protect of the consequences of UV-mediated photooxidation. The last section is devoted to the development of strong antioxidant oral compounds and discusses their possibilities as adjuvants in skin protection and repair and regeneration.

Keywords: Photoprotection, sunscreens, oral antioxidants, dietary photoprotectants.