The results of artificial polyploidization for horticultural and agronomic plant species are presented in this review.
The data on use of the classical antimitotic drug colchicine for chromosome doubling are reported. The efficacy of
other compounds such as dinitroanilines and phosphorothioamidates in polyploidy induction as compared to colchicine
has been summarized. The molecular basis of highly specific binding of dinitroanilines and phosphorothioamidates with
plant tubulin for induction of efficient polyploidy are discussed.