1 Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
2 Caspian Digestive Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
Strongyloidiasis is self-limited by the complete immune system, it may be complicated and causes hyperinfection in immunocompromised patients. Objective: Here, we report a case of an immunocompromised patient with duodenal involvement of Strongyloides stercoralis.
A 65-year-old man presented with severe pain in central abdomen and periumbilical regions. He had no history of alcohol consumption, smoking and surgery but the history of RA (Rheumatoid Arthritis) and hypothyroidism taking immunosuppressive medications. The patient underwent endoscopy and colonoscopy which pathological analysis of the biopsies revealed remarkable findings in favor of Strongyloidiasis. After two consecutive day’s consumption of ivermectin 200µg/kg, the symptoms were completely removed. Also, the stool examination was negative for S. stercoralis larvae two weeks after end of the treatment.
It seems that in immunocompromised patients with gastrointestinal symptoms assumption of parasite-like infections such as Strongyloidiasis should be considered as one of the diagnosis options. Due to the physiological and gut microbial alternations, these patients are more susceptible to infectious diseases.
Keywords: Colonoscopy, Gut microbiome, Hyperinfection, Ivermectin, Rheumatoid arthritis, Strongyloides stercoralis.
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* Address correspondence to this author at the Caspian Digestive Diseases Research Center CDDRC, Guilan University of Medical Sciences GUMS, Razi Hospital, Sardar-Jangle Ave., P.O. Box: 41448-95655, Rasht, Iran; Tel: +981333534951; Fax: +981333535116; E-mail: firstname.lastname@example.org