Abstract HTML Views: 267 PDF Downloads: 123 Total Views/Downloads: 615
Abstract HTML Views: 161 PDF Downloads: 98 Total Views/Downloads: 391
Rationale and aim:
Upper airway disorders, like allergic and non-allergic rhinitis, are common nasal conditions
affecting millions of individuals worldwide. The prevalence of allergic rhinitis (AR), in particular, has been increasing in
the last decades. The pervasiveness of this disorder therefore imposes a large burden both on individual patients and the
society. A wide range of drugs exists for symptomatic treatment of rhinitis, such as corticosteroids, decongestants, and antihistamines,
but standard therapies are often associated with several side effects. A new class of medical devices, based
on bio-mechanically innovative triggers, has been proven to have a good clinical effectiveness with lower adverse reactions,
particularly over prolonged administration periods.
The present study aims at evaluating the economic impact of rhinitis, with respect to direct and indirect costs, and analysing
the use of the medical device Narivent® compared to standard therapies to manage the symptoms of this illness.
Via a Monte Carlo simulation study, data on disease prevalence, drug prescription and cost of both the specific
therapeutic approach and the adverse events treatment will be combined to provide an estimate of the overall cost of the
pharmacotherapy as compared with Narivent®
Lowering the impact of adverse reactions related to standard therapy through the use of novel therapeutic approaches
like Narivent®, might reduce the overall burden of rhinitis by about 5 billion per year.
The use of the medical device Narivent®, as an alternative approach to manage symptoms associated with
rhinitis, may contribute to bring down its costs by about 3.5% yearly as compared to the standard therapy.