1 Department of Internal Medicine, Holbæk Hospital, Holbæk, Denmark
2 Department of Clinical Microbiology, Slagelse Hospital, Slagelse, Denmark
3 Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
4 Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark
5 Institute of Clinical Medicine, University of Copenhagen, Denmark
Cardiobacterium hominis and Cardiobacterium valvarum are well known, though rare, etiologic agents of infective endocarditis. Cardiac devices are increasingly implanted.
Two cases of infective episodes in pacemaker (PM) treated patients with respectively C. hominis and C. valvarum are presented. In one case blood-culture bottles yielded growth of C. hominis at two episodes with two years apart. At the second episode a vegetation was recognized at the PM lead and the PM device and lead was removed. In the C. valvarum case, echocardiography revealed a bicuspid aortic valve with severe regurgitation and a more than 1 cm sized vegetation.
The cases illustrate the diversity in disease severity by Cardiobacterium species. Careful follow up has to be performed in order not to overlook a relatively silent relapsing infection.
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* Address correspondence to this author at the Department of Clinical Microbiology, Slagelse Hospital, Ingemannsvej 46, 4200 Slagelse, Denmark; Tel: +4558559421; Fax: +4558559410; E-mail: firstname.lastname@example.org