RESEARCH ARTICLE
Effect of Solvents on Phytochemicals Content and Antioxidant Activity of Ganoderma lucidum
Moyen Uddin Pk1, 2, 3, Rabiul I. Talukder3, Mohammad K. I. Sarkar4, *, Tasnia Rahman4, Rumana Pervin5, Matiar Rahman5, Elina A. Zenat6, Lima Akther7
Article Information
Identifiers and Pagination:
Year: 2019Volume: 13
First Page: 10
Last Page: 15
Publisher ID: TOMICROJ-13-10
DOI: 10.2174/1874285801913010010
Article History:
Received Date: 16/10/2018Revision Received Date: 10/12/2018
Acceptance Date: 18/12/2018
Electronic publication date: 31/01/2019
Collection year: 2019
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Introduction:
The aim of this study was to assess the induction of solvents on the total phenol and flavonoid content and also the antioxidant activity of Ganoderma lucidum extracts.
Materials & Methods:
In this study, two concentrations (100% and 75%) of diethyl ether, ethanol, butanol, chloroform, and acetone were used as extractants of Ganoderma lucidum. Total phenol and flavonoid contents were measured by spectrophotometric methods and 1, 1-diphenyl-2-picrylhydrazyl (DPPH). Free radical scavenging assay was used for the investigation of antioxidant activity.
Results & Discussion:
Extractants significantly affected the % yield of extract, the quantity of phenol and flavonoids and antioxidant activity of Ganoderma lucidum mushroom. The highest extraction yield, around 38%, was achieved by 75% acetone, followed by 100% acetone (about 36%) and 75% chloroform (approximate 21%). Hydro-acetone extract exhibited the most significant antioxidative properties (EC50 value; 645.55 µg/mL) comprised of a higher total of phenol content. In conclusion, the total phenol content encouraged the antioxidative potential of Ganoderma lucidum mushroom.
Conclusion:
These findings indicate that the selective extraction of Ganoderma lucidum shows significant biological activities.