The Open Neuroimaging Journal




ISSN: 1874-4400 ― Volume 13, 2019

Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls



Mira A. Coleman1, Jane Matsumoto2, Carrie M. Carr2, Laurence J. Eckel2, Amulya A. Nageswara Rao3, *
1 Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, Mayo Clinic, Rochester, Minnesota, USA
2 Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA
3 Department of Pediatric and Adolescent Medicine/Division of Pediatric Hematology-Oncology, Mayo Clinic, Rochester, Minnesota, USA

Abstract

Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder with an unpredictable clinical course and highly varied clinical presentation ranging from single system to multisystem involvement. Although head and neck involvement is common in LCH, isolated bilateral temporal bone involvement is exceedingly rare. Furthermore, LCH is commonly misinterpreted as mastoiditis, otitis media and otitis externa, delaying diagnosis and appropriate therapeutic management. To improve detection and time to treatment, it is imperative to have LCH in the differential diagnosis for unusual presentations of the aforementioned infectious head and neck etiologies. Any lytic lesion of the temporal bone identified by radiology should raise suspicion for LCH. We hereby describe the radiologic findings of a case of bilateral temporal bone LCH, originally misdiagnosed as mastoiditis.

Keywords: Langerhans cell histiocytosis, Bilateral temporal bone, Mastoiditis, CT, MRI.


Article Information


Identifiers and Pagination:

Year: 2013
Volume: 7
First Page: 53
Last Page: 57
Publisher Id: TONIJ-7-53
DOI: 10.2174/1874440001307010053

Article History:

Received Date: 19/9/2013
Revision Received Date: 23/12/2013
Acceptance Date: 26/12/2013
Electronic publication date: 30/12/2013
Collection year: 2013

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© Coleman et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.


* Address correspondence to this author at the Mayo Clinic, 200 First Street S.W., Rochester, MN 55905, USA; Tel: 507-284-2695; Fax: 507-284-0727; E-mail: nageswararao.amulya@mayo.edu


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