The Open Ophthalmology Journal

ISSN: 1874-3641 ― Volume 13, 2019

Predictive Factors for Successful High Myopia Treatment Using High-Frequency Laser-In-Situ Keratomileusis

Widya Artini1, 2, *, Setyo B. Riyanto2, Johan A. Hutauruk2, Tjahjono D. Gondhowiardjo1, 2, Aria Kekalih3
1 Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Kirana Hospital, Jakarta, Indonesia
2 Jakarta Eye Center Menteng Jakarta, Jakarta, Indonesia
3 Community Medicine Department, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia



To evaluate the predictive factors of LASIK procedure for high myopia with or without astigmatism using a combination of high-frequency femtosecond-assisted LASIK followed by an excimer laser.


This study was a retrospective interventional case series study to evaluate myopic eyes undergoing high platform LASIK with FEMTO LDV Z2 intervention, followed by WaveLight®EX500 excimer laser machine. Subjects were divided into 2 groups: high myopia (SE of -6.01 to -9.00 D) and very high myopia (SE of -9.01 D or higher). Myopic eyes (Spherical Equivalent/SE) less than –13 D were included in this study. Visual Acuity (VA) was evaluated 1 day and 60 days after the procedure. Predictive factors, such as age, degree of sphere, degree of astigmatism, keratometric reading and axial length were analyzed to detect any influences affecting the final VA results.


A total of 316 myopia eyes underwent intervention, mean age: 25.3±3.8 years. Target treatment was achieved in 96.1% of patients with high myopia and 69.9% of patients with very high myopia. High degree of sphere and astigmatism constitutes an important factor influencing final VA.


Modern machines provide a more promising efficacy and success of LASIK procedure in high myopia: important predictive factors were a high degree of sphere and astigmatism for achieving the optimal final outcome.

Keywords: Laser-in-situ keratomileusis, Femtosecond laser, Excimer laser, High myopia, Astigmatism, Predictive factors.

Article Information

Identifiers and Pagination:

Year: 2018
Volume: 12
First Page: 214
Last Page: 225
Publisher Id: TOOPHTJ-12-214
DOI: 10.2174/1874364101812010214

Article History:

Received Date: 30/04/2018
Revision Received Date: 18/5/2018
Acceptance Date: 5/7/2018
Electronic publication date: 23/7/2018
Collection year: 2018

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© 2018 Artini et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: ( This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Kirana Hospital, Jakarta, Indonesia; Tel: +62811841010 E-mail:


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