The Open Orthopaedics Journal

ISSN: 1874-3250 ― Volume 14, 2020

Is it Possible to Recover Cardiac Functions After Total Knee Arthroplasty?

Aydın Arslan1, *, Bilal Çuglan2, Bülent Özkurt3, Ali Utkan3, Mehmet Fatih Korkmaz3, Tuba Tülay Koca4, Resit Sevimli3
1 Department of Orthopaedics and Traumatology, Elite İstanbul Medical Center, Istanbul Gelisim University, Istanbul, Turkey
2 Department of Cardiology, Silivri Medical Park Hospital, Bahcesehir University, Istanbul, Turkey
3 Department of Orthopaedics and Traumatology, Ankara Numune Research and Training Hospital, SBU, Ankara, Turkey
4 Department of Orthopaedics and Traumatology, Turgut Ozal Medical Center, Malatya, Turkey



Patients suffering from knee osteoarthritis lead a less active life than their healthy peers. It is well known that insufficient physical activity is the most common cause of chronic diseases. However, there is not enough research to enlighten the effect of increased functional capacity on cardiac functions after Total Knee Arthroplasty (TKA). This study aimed to investigate whether the orthopedic surgeons can predict that the patients will be healthier after TKA in terms of cardiac functions or not?


109 patients who underwent TKA were prospectively followed for one year. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and short form 36 (SF-36) surveys, BMI measures, average step count per day, the six-minute walking test (6MWT), the Five-Times-Sit-to-Stand Test (FTSST) and Doppler echocardiography were performed both in the preoperative and postoperative period.


After TKA, there was a substantial improvement in terms of WOMAC and SF36 survey scores. The average step count increased from 2199.6±690.8 steps/day to 4124.3±1638.8 steps/day. 6MWT and FTSST improved significantly as well. The average brisk walking time was 174.23±95.11 minutes/week. The means of early and late mitral inflow velocity ratios (E/A and Em/Am ratios) increased from 0.71±0.12 to 0.77±0.13 and from 0.66±0.13 to 0.76± 0.15 at the first year follow-up visit, respectively (p<0.001).


In the first year, objective physical capacity measures increased together with the expected improvements in disease-specific and generic measures. After TKA, left ventricular diastolic functions may be considered to have recovered in the light of the healing signs via echocardiography.

Article Information

Identifiers and Pagination:

Year: 2018
Volume: 12
First Page: 261
Last Page: 268
Publisher Id: TOORTHJ-12-261
DOI: 10.2174/1874325001812010261

Article History:

Received Date: 16/4/2018
Revision Received Date: 21/6/2018
Acceptance Date: 21/6/2018
Electronic publication date: 19/7/2018
Collection year: 2018

© 2018 Arslan et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: ( This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Orthopaedics and Traumatology, Elite İStanbul Medical Center, Istanbul Gelisim University, Istanbul, Turkey; Tel: +9005072311411; E-mail:

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