The Open Public Health Journal

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Epidemiological and Clinical Characteristics of Patients with COVID-19 in Arak, Iran

Morteza Mousavi-Hasanzadeh1, Hossein Sarmadian2, #, Fatemeh Safi3, Mohammad Jamalian4, Amir Almasi-Hashiani5, *
1 Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran
2 Department of Infectious Diseases, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran
3 Department of Radiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran
4 Department of Toxicology, School of Medicine, Arak University of Medical Sciences, Arak, Iran
5 Department of Epidemiology, School of Health, Arak University of Medical Sciences, Arak, Iran



The number of confirmed cases of COVID-19 is increasing. Here we present the clinical characteristics and outcomes of COVID-19 in Arak, Iran.


In this study, 139 COVID-19 confirmed cases from 15 February to 15 March 2020 in Arak, Iran, were investigated. The clinical signs, symptoms, laboratory and radiological findings and outcomes were analyzed.


The mean age of the patients was 55.41 years (S.D.: 17.11) and 55.40% of them were males. 26.81% of patients had recently traveled to other epidemic cities. The most common clinical manifestations were fever (71.64%), cough (67.16%), shortness of breath (55.22%), muscle ache (50.00%) and the most prevalent complications were taste and smell disruption (29.5%), weakness (22.3%), anorexia (20.1%) and acute respiratory distress syndrome (ARDS) (15.8%). Almost half of the patients had lymphopenia, an elevated level of erythrocyte sedimentation rate (ESR) and C - reactive protein (CRP). In terms of outcome, 9.3% of patients needed an ICU admission as a result of ARDS in which 15.32% were directly admitted to the ICU. 43.2% of patients have been discharged and the case fatality rate (CFR) was estimated as 11.5%.


COVID-19 pneumonia usually occurred at an age older than 50 years and in the male gender. The most common initial clinical laboratories and radiological presentations are fever, cough, lymphopenia with elevated CRP and ESR and Bilateral mixed ground-glass opacities with consolidation.

Keywords: COVID-19, Epidemiology, Case Fatality Rate, Acute Respiratory Distress Syndrome, ICU, Epidemiology.

Article Information

Identifiers and Pagination:

Year: 2020
Volume: 13
First Page: 712
Last Page: 717
Publisher Id: TOPHJ-13-712
DOI: 10.2174/1874944502013010712

Article History:

Received Date: 03/07/2020
Revision Received Date: 13/10/2020
Acceptance Date: 21/10/2020
Electronic publication date: 31/12/2020
Collection year: 2020

© 2020 Mousavi-Hasanzadeh et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Department of Epidemiology, School of Health, Arak University of Medical Sciences, Arak, Iran; Tel: 0912 706 7291; E-mails:;

#Contributed equally to this work

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