Abstract:

A current phenomenon of great concern among the medical communities in developing countries is rising multi-drug resistant organisms, and the challenges of curing the infections in children. In this study, we evaluated the multi drug resistant strains of Escherichia coli isolated from urinary tract infection in children in southern Iran. Totally, 90 strains of E. coli were collected from urine samples of the children, aged from 1 month to 14 years, referred to Motahary Hospital of Jahrom, Iran. After confirmation of the urine cultures which were expressive of urinary infection, gram stain and biochemical differential test were done for the isolates and their susceptibility patterns to different antibiotics were determined by standard disk diffusion method. The antibiogram patterns of the isolates showed a high percentage of multi drug resistance to ampicillin, co-trimoxazole and tetracycline which was repeated among 13 strains. With regard to the present data and high percentage of multi drug resistant strains of E coli, regular monitoring antimicrobial drug resistance in different areas is necessary to prevent unsuitable utilization of drugs which is responsible for the emerging multi drug resistant strains.