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Preliminary screening study revealed that the methanolic extract of the stem of T. indica showed xanthine
oxidase inhibitory activity in a concentration-dependent manner. EA fraction was selected to be further study due to its
potential to inhibit xanthine oxidase enzyme with IC50 value of 21.14 μg/ml which in lower than IC50 value of MeOH
extract, 42.02 μg/ml. Further separation and purification of EA fraction led to the isolation of two known compounds.
Those compounds were identified by analysis of their spectroscopic data and comparisons with literature data to be
betulinic acid and 5,7-dihydroxyl-8-methoxyflavone.