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The purpose of this study was to isolate and identify compounds from the bark of Alseodaphne perakensis (Lauraceae) which
commonly known as Medang to validate and evaluate the use of this species in antimalaria activity. The comprising compounds
from the dichloromethane crude extract were separated using column chromatography and the structures of the compounds
were elucidated using spectroscopic analysis. The identified compounds were aporphine alkaloids; corydine 1 and
oxohernagine 2. These isolated compounds show IC50 values 0.404µg/ml and 0.738µg/ml, respectively against Plasmodium
falciparum, K1 isolate (resistant strain).