Melastoma Malabatricum is a local shrub, commonly known as senduduk that belongs to the family of Melastomataceae. The
aim is to evaluate the potential anticancer activities of the different extracts from M. malabathricum. In this study, petroleum
ether and chloroform were used in the extraction of stems and flowers of M. malabathricum. The extracts were tested for
cytotoxic activity against skin melanoma cancer cell lines (A375) and cervical cancer cell lines (HeLa). Petroleum ether
extracts of stem (PeMMS) showed significant growth inhibition of A375 cell lines, followed by the extract of flower (PeMMF).
Meanwhile, PeMMF showed less significant growth inhibition of HeLa cell lines, followed by PeMMS. As for the chloroform
extracts of stem (CHMMS) and flower (CHMMF), it does not inhibit the growth of both cell lines.