Detailed investigation on leaves and bark of Artocarpus elasticus has led to the isolation of eight flavonoids derivatives
including four new compounds, artoelastil (1), artoelastidi (2), artoelastiq (3), and artoelastidi (4) together with four known
compound identified as cycloartocarpesin (5), artonin E (6), cycloartobiloxanthone (7) and artobiloxanthone (8). The structural
elucidations of the pure compound were carried out using spectroscopic methods such as UV, IR, NMR, MS and also by
comparison with published data. The compounds were tested for their biological activities on antioxidant, cytotoxic, and
antimicrobial activities using standard method. Some of the isolated compounds exhibited interesting biological activity which
can be further developed as potential antimicrobial, antioxidants and cytotoxic agents.