Phytochemistry investigation on alkaloids from Alseodaphne pendulifolia Gamb. yielded 3 types of aporphines; Hernagine 1,
N-methylhernagine 2, and Oxohernagine 3. Preliminary screening on alkaloids crude extract from this species exhibited an
antiplasmodial activity (0.804μg/ml IC50) against Plasmodium falciparum, K1 isolate (resistant strain). Further investigation on
isolated compound were found to possess antiplasmodial activity (0.738 - 1.814μg/ml IC50). This study involves extraction,
separation by using various chromatography methods and structural elucidation by spectroscopic technique such as IR, NMR
including 1D, 2D-NMR and MS.