Fasihuddin B. Ahmad, Zaini B Assim, Ismail B. Jusoh, Hamzah Mohd. Salleh, Laily B. Din
Bioenvironmental Engineering Research Centre (BERC), Biotechnology Engineering Department, Faculty of
Engineering, International Islamic University Malaysia (IIUM), P.O. Box 10 Jalan Gombak, Kuala Lumpur, 50728, Malaysia.
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The leaf, bark and root oils of Goniothalamus cylindrostigma were obtained by hydrodistillation method and investigated by
capillary GC and GC/MS. The chemical components were identified by comparison of their mass spectral data with those
existing in the Wiley library, their retention indices and co-chromatography of some constituents with authentic samples. The
oils and several reference compounds were further evaluated for their antimicrobial activity using broth microdilution methods.
The bark and root oils were qualitatively similar but with some variation in levels of the individual constituents, with geranyl
acetate as the most abundant compounds. The bark oil contained a higher amount of geranyl acetate (41.5%), geraniol (20.5%)
and linalool (8.6%) than the root oil. However, the major group of compounds in the leaf oil of G. cylindrostigma was
dominated by monoterpenoids and terpinen-4-ol (38.9%) and 1,8-cineole (17.7%) were the important representatives. The
antimicrobial activity results showed that the essential oils of G. cylindrostigma exhibited strongest inhibitory activity against S.
epidermidis and Candida albicans. Based on the results of the assay on standard samples, compounds such as geranyl acetate,
geraniol, linalool and terpinen-4-ol in the oils might be responsible for the high antimicrobial activity.