Abstract:

The chemistry of the Rauvolfia species has been comprehensively investigated for the presence of different types of compounds like alkaloids, ferulic acid ester derivatives, terpenoids and their biological activities over a long period of time. For examples the clinical uses of Rauvolfia in arterial hypertension has been described in 1955 and the root and bark of Rauvolfia yunnanensis has been used for the remedy of snake bites, feverish illnesses and insanity in China and India. In this study, bioactive compounds have been isolated from Rauvolfia reflexa (Apocynaceae). Twelve compounds were isolated from the bark and leaves of Rauvolfia reflexa, and the structural elucidation of the isolated compounds has been performed using spectral method such as UV, IR, MS, 1D and 2D NMR. The Anti-Alzheimer and Antioxidant activities studies were also carried out on the crude extracts and pure compounds.