The Open Plant Science Journal




(Discontinued)

ISSN: 1874-2947 ― Volume 11, 2019
RESEARCH ARTICLE

Chemical Constituents from the Rhizomes of Cyperus Rotundus L.



Shahnaz Sultana1, 2, Mohammed Ali1, *, Showkat Rasool Mir1
1 Phytochemistry Research Laboratory, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110 062, India .
2 College of Pharmacy, Jazan University, Jazan, Saudi Arabia.

Abstract

Background:

Cyperus rotundus L. (Cyperaceae), is a perennial sedge distributed throughout India and other parts of the world. Its tubers are used as an appetizer, febrifuge and to treat bleeding, blisters, boils, cough, diarrhea, inflammation, lacteal disorders, rheumatoid arthritis, stomach ailments, skin rashes, thirst, vomiting, worm infestation and wounds.

Objective:

Our study was planned to isolate chemical constituents from the rhizomes of C. rotundus and to characterized their structures.

Method:

The air-dried rhizome powder was exhaustively extracted with methanol in a Soxhlet apparatus. The concentrated methanol extract was adsorbed on silica gel (60-120 mesh) for the preparation of a slurry. The dried slurry was chromatographed over silica gel column packed in petroleum ether. The column was eluted with petroleum ether, chloroform and methanol, successively, in order of increasing polarity to isolate the compounds.

Results:

Phytochemical investigation of the tubers led to isolate a sesquiterpenone characterized as 12-methyl cyprot-3-en-2-one-13-oic acid (1), two aliphatic ketone viz. n-dotriacontan-15-one (2) and n-tetracontan-7-one (8), fatty esters n-pentadecanyl octadec-9, 12- dienoate (n-pentadecanyl linoleate, 3), n-hexadecanyl linoleate (4), n-hexadecanyl oleate (5) and n-pentacos-13ʹ-enyl octadec-9-enoate (n-pentacos-13ʹ-enyl oleate, 9), two steroidal esters stigmast-5,22–dien-3β –olyl n-dodecanoate (stigmasterol laurate, 6) and stigmast-5, 22-dien-3β-olyl n-tetradecanoate (stigmasterol myristate, 7), β-sitosterol-3β-O-glucoside (10) and a triterpenic glycosidic ester lup-12, 20 (29)-dien-3β-ol-3-α-L-arabinopyranosyl-2'-oleate (lupenyl 3β-O-arabinpyranosyl 2′-oleate, 11). The structures of these compounds were established by spectral data analysis and chemical reactions.

Conclusion:

A sesquiterpene identified as cyprot-3-en-2-one-14-oic acid, two aliphatic ketones, fatty esters, two steroidal esters, β-sitosterol-3β-O-glucoside and lupenyl 3β-O-arabinpyranosyl 2′-oleate were isolated for the first time from the rhizomes.

Keywords: Cyperus rotundus, Tubers, Acyl esters, Aliphatic ketones, Sterol esters, Lupenyl, Glycoside, Structure elucidation.


Article Information


Identifiers and Pagination:

Year: 2017
Volume: 10
First Page: 82
Last Page: 91
Publisher Id: TOPSJ-10-82
DOI: 10.2174/1874294701710010082

Article History:

Received Date: 28/02/2017
Revision Received Date: 11/05/2017
Acceptance Date: 15/05/2017
Electronic publication date: 25/08/2017
Collection year: 2017

© 2017 Sultana et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


* Address correspondence to this author at Phytochemistry Research Laboratory, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India; Tel: +9968281082; E-mail: maliphyto@gmail.com.


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