1 Departments of Urology and Renal Transplantation, Yokohama City University Medical Center, Yokohama, Japan
2 Department of Urology, Reproduction Center, Yokohama City University Medical Center, Yokohama, Japan
3 Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
4 Department of Urology, Yokohama City University Medical Center, Yokohama, Japan
Renal transplantation is a useful option for allowing female renal failure patients of childbearing age to achieve pregnancy. However, there have been a few reports on the effects of renal transplantation on infertility treatment in male renal failure patients. We herein report two cases in which male patients underwent infertility treatment after renal transplantation.
Case 1: A 51-year-old Asian (Japanese) man underwent transplantation (the donor was his wife) for renal failure due to Autosomal Dominant Polycystic Kidney Disease (ADPKD). At two years after transplantation, he visited the reproduction center in our institute due to infertility. A semen analysis revealed oligoasthenozoospermia. He ultimately failed to achieve pregnancy and gave up on infertility treatment.
Case 2: A 47-year-old Asian (Japanese) man underwent renal transplantation (the donor was his sister) due to renal failure caused by diabetes mellitus. At three years after renal transplantation, he visited the reproduction center in our institute for infertility. Due to ejaculation disability and the absence of sperm in the patient’s urine after masturbation, he was diagnosed with anejaculation. Thus, testicular sperm extraction (TESE) was performed. Twenty-three motile spermatozoa were successfully retrieved by microdissection TESE (micro-TESE). ICSI was subsequently performed and a good embryo was transferred. His wife achieved pregnancy and is expected to deliver this October.
We report two cases of male infertility treatment after renal transplantation.
Keywords: Male infertility, azoospermia, oligospermia, Renal transplantation, Spermatozoa, Kidney disease.
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* Address correspondence to this author at the Departments of Urology and Renal Transplantation, Yokohama City University Medical Center, Yokohama, Japan; Tel: +81-45-786-5775; E-mail: firstname.lastname@example.org