CASE REPORT
The Treatment of Male Infertility After Allograft Renal Transplantation: A Case Series
Daiji Takamoto1, Takashi Kawahara1, *, Teppei Takeshima2, Shinnosuke Kuroda2, Taku Mochizuki1, Kazuhide Makiyama4, Yasushi Yumura1, Jun-ichi Teranishi1, Hiroji Uemura1
Article Information
Identifiers and Pagination:
Year: 2019Volume: 12
First Page: 1
Last Page: 3
Publisher ID: TOUNJ-12-1
DOI: 10.2174/1874303X01912010001
Article History:
Received Date: 15/11/2018Revision Received Date: 28/1/2019
Acceptance Date: 02/02/2019
Electronic publication date: 28/02/2019
Collection year: 2019
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Background:
Renal transplantation is a useful option for allowing female renal failure patients of childbearing age to achieve pregnancy. However, there have been a few reports on the effects of renal transplantation on infertility treatment in male renal failure patients. We herein report two cases in which male patients underwent infertility treatment after renal transplantation.
Case Presentation:
Case 1: A 51-year-old Asian (Japanese) man underwent transplantation (the donor was his wife) for renal failure due to Autosomal Dominant Polycystic Kidney Disease (ADPKD). At two years after transplantation, he visited the reproduction center in our institute due to infertility. A semen analysis revealed oligoasthenozoospermia. He ultimately failed to achieve pregnancy and gave up on infertility treatment.
Case 2: A 47-year-old Asian (Japanese) man underwent renal transplantation (the donor was his sister) due to renal failure caused by diabetes mellitus. At three years after renal transplantation, he visited the reproduction center in our institute for infertility. Due to ejaculation disability and the absence of sperm in the patient’s urine after masturbation, he was diagnosed with anejaculation. Thus, testicular sperm extraction (TESE) was performed. Twenty-three motile spermatozoa were successfully retrieved by microdissection TESE (micro-TESE). ICSI was subsequently performed and a good embryo was transferred. His wife achieved pregnancy and is expected to deliver this October.
Conclusion:
We report two cases of male infertility treatment after renal transplantation.
