Division of Nephrology, Children's National Medical Center, The George Washington University School of Medicine
and Healthy Sciences, Washington, DC, USA
Glomerulonephritis [GN] is one of the common acquired pediatric renal disorders encountered in clinical
practice. The clinical manifestations include gross or microscopic hematuria, proteinuria, and nephrotic syndrome. Renal
dysfunction and hypertension may also be present in many patients. Etiopathogenesis of GN can be idiopathic in a large
majority, while some may result from infections or known immune disorders. Several of these disorders are now believed
to arise from dysfunctions of podocytes and are grouped under the heading of “podocytopathies”. This review focuses on
the clinical manifestations and management of the common forms of acute GN encountered in children.
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* Address correspondence to this author at The Division of Nephrology,
Children's National Medical Center, The George Washington University
School of Medicine and Health Sciences, Washington, DC, USA; Tel: 202-
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