Table 3:
IC
50
Values (in nM) of Inhibitors in the Three Trk Assays
TrkA
TrkB
TrkC
NGF
Thaps
BDNF
Thaps
NT-3
Thaps
K252a
13
570
*
11
>1000
30
500
*
AG879
1326
112
1011
51
1308
231
GW44176
231
2831
*
141
8205
*
460
8970
*
*
Values may not be accurate as the curves did not reach saturation.