Fig. (7) Radial plot of the inhibition of 1 µM BAY-43-9006 against 231 kinases using the FRET-based assays. For each of the six areas numbered, kinases represented within each area and the percent inhibition observed are listed. Area 1: RET (77%), RET V804L (44%), and RET Y791F (80%). Area 2: VEGFR2 (48%), VEGFR3 (40%), and FMS (40%). Area 3: FLT3 (89%), FLT3 D835Y (45%), and PDGFR α (33%). Area 4: PDGFR α V561D (101%). Area 5: C-RAF (50%), B-RAF (13%), and B-RAF V599E (71%). Area 6: HIPK4 (45%).