Table 2: A Selection of the Molecular Imaging Probes Made or Being Made, their Intended Application, and the NIH Institute Initializing the Request

Composition(s)	Refs	Detectable Agent(s)	Indication(s)	NIH Institute
Biarsenicals	[14]	Fluorescent protein	Prion infection studies	NIAID
Thyroid hormones	[15]	Radioiodine	Thyroid disorders	NIDCD
Affibody® molecules	[16]	Multiple	Cancer	NCI
Enzyme substrate	[17]	Fluorescent	PI-PLC	NHLBI
Dendrimer complexes	[18]	Gadolinium	Vascular studies	NCI
Caged glutamate	[19]	Fluorescent	Receptor activation	NINDS
Cholesterol derivatives	[20]	Fluorescent	Lipid rafts	NIEHS
Chelate complexes	[21]	Fluorescent	Lifetime modulation	NICHD
Receptor binding agents	[22]	MRI	Breast cancer imaging	NCI
Nucleotide analogs	[23]	Fluorescent	DNA/RNA probes	NCI
Adenosine analogs	[24]	Radioiodine	Receptor agents	NIDDK
Nitroxides	[25]	MRI	Radiation damage	NCI
Caged molecules	[26]	Fluorescent	Intracellular trafficking	NICHD
Dopamine antagonists	[27]	Radiolabeled	Neurological disorders	NIDA
Liposomes	[28]	Multiple	Colon cancer	CC
Dendrimer complexes	[29]	MRI	Gliomas	NCI
Proteins	[30]	Radiolabeled	Amyloid diseases	NIAMS
Receptor binding agents	[31]	Fluorescent	Calcium channel agents	NIA
Gold nanoparticles	[32]	X-ray	HIV-1 binding sites	NCI
Chelate complexes	[33]	Gadolinium	Neural trafficking	NIMH
Nucleotides	[34]	Fluorescent	HIV-1 studies	NCI
Peptides	[35]	Radiolabeled	Receptor studies	NIMH
Receptor binding agents	[3]	Fluorescent	Lysosomal diseases	NHGRI