D1CT Tg, transgenic mouse line in which neuropotentiating cholera toxin is expressed under the D1-type dopamine receptor promoter elements;
Hoxb8 mutant, homozygous loss-of-function for mammalian transcription factor Hoxb8;
5-HT2C null, null mutant mouse for the 5-HT
2C subtype of the serotonin receptor; ArKO (for aromatase knock-out), estrogen deficient mouse line resulting from elimination of aromatase expression; DAT KD, dopamine transporter knock-down mice with DAT levels reduced to 10% of wild-type values;
SAPAP3 null, null mutant mouse for the postsynaptic scaffolding protein SAPAP3.
* Note that face validity incorporates both behavioral similarity AND specificity.
^ CSTC circuit expression refers to the extent to which the gene or Tg is expressed in these brain regions.
nd - not demonstrated.