Fig. (1) Comparison of OATP1B1- and OATP1B3-mediated transport of fluorescent substrates. Uptake was measured with 1 µM of the indicated fluorescent compounds on 24-well plates for 30 min. Values are means ± SE of two combined independent experiments each performed with triplicate determinations. FMTX: fluorescein methotrexate; AMTX: Alexa Fluor® 488 methotrexate; Flutax-2: Oregon Green® 488 Taxol; WT: wild-type CHO cells; OATP1B1: CHO cells expressing OATP1B1; OATP1B3: CHO cells expressing OATP1B3.