Table 1: Statistics of Prestwick Library Screening
OATP1B1 |
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|
Plate number |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
13 |
14 |
Mean (neg control) |
5,170 |
5,906 |
5,428 |
7,400 |
6,166 |
4,984 |
4,866 |
6,113 |
5,670 |
6,713 |
6,390 |
6,054 |
6,042 |
9,159 |
STDEV (neg control) |
390 |
1,107 |
807 |
924 |
579 |
645 |
451 |
721 |
634 |
1,150 |
425 |
605 |
444 |
921 |
Mean (pos control) |
9,411 |
10,044 |
9,499 |
14,100 |
10,904 |
9,080 |
8,950 |
11,267 |
10,641 |
11,879 |
12,990 |
12,183 |
14,967 |
16,572 |
STDEV (pos control) |
871 |
715 |
753 |
1,520 |
1,267 |
803 |
537 |
1,042 |
935 |
1,663 |
954 |
1,226 |
1,249 |
1,760 |
Sample mean |
9,654 |
10,381 |
9,101 |
13,350 |
9,857 |
8,448 |
8,967 |
11,136 |
10,397 |
11,423 |
12,343 |
11,735 |
12,785 |
16,997 |
Z' factor |
0.11 |
-0.32 |
-0.15 |
-0.09 |
-0.17 |
-0.06 |
0.27 |
-0.03 |
0.05 |
-0.63 |
0.37 |
0.10 |
0.43 |
-0.08 |
OATP1B3 |
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|
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|
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|
|
|
Plate number |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
13 |
14 |
Mean (neg control) |
7,161 |
8,034 |
7,766 |
10,591 |
7,901 |
7,506 |
7,734 |
9,639 |
8,273 |
8,231 |
8,418 |
9,093 |
9,047 |
9,856 |
STDEV (neg control) |
760 |
1,315 |
1,037 |
1,814 |
523 |
834 |
1,194 |
1,495 |
761 |
332 |
370 |
472 |
570 |
1,026 |
Mean (pos control) |
26,768 |
31,694 |
27,097 |
31,987 |
28,351 |
25,272 |
30,369 |
26,319 |
26,882 |
30,781 |
31,653 |
34,132 |
34,603 |
32,986 |
STDEV (pos control) |
1,704 |
2,889 |
1,778 |
1,212 |
1,789 |
2,271 |
2,257 |
1,792 |
1,171 |
4,063 |
1,281 |
3,003 |
3,917 |
3,014 |
Sample mean |
26,308 |
26,850 |
23,819 |
33,715 |
26,838 |
25,368 |
25,738 |
29,565 |
26,661 |
29,799 |
29,365 |
33,188 |
31,714 |
36,503 |
Z' factor |
0.62 |
0.47 |
0.56 |
0.58 |
0.66 |
0.48 |
0.54 |
0.41 |
0.69 |
0.42 |
0.79 |
0.58 |
0.47 |
0.48 |